Sequence, molecular data, research status and testing standards for AOD-9604, written for Canadian researchers.
AOD-9604 is a synthetic peptide based on the tail end (amino acids 177 to 191) of human growth hormone, with a tyrosine added at the start for stability. It was designed to keep a fat-metabolism region of the hormone without its other effects.
AOD-9604 was developed in Australia in the late 1990s and studied in clinical trials for obesity. It did not progress to authorization as a drug. It is discussed in research settings as a fragment that does not act on the growth hormone receptor in the same way as the full hormone.
What it is: A small piece copied from the tail end of human growth hormone.
The plain-English story: Human growth hormone is a long, famous script. AOD-9604 is just the last page, torn out and rehearsed on its own. The hope was to keep the 'fat-burning' lines and drop the growth lines. In early studies the audience was not impressed, and it never became an approved medicine. It lives on mostly in sellers' marketing, not in doctors' offices.
What it does in the body: The thinking was to keep the part linked to fat breakdown and leave out the growth effects.
What researchers are looking at: Tested for weight loss in early studies, but it did not become an approved medicine.
What you may hear online: Videos often call it a fat-burning peptide.
The straight story: Early studies did not lead to an approved medicine.
The catch (where it stands in Canada): Not an approved medicine in Canada, so nobody can legally sell it to you as one. Also banned in sport.
Educational information only. Not medical advice, and not a claim that this peptide is safe or effective for any use.
Peptide Authority summarizes published research for educational purposes only. Nothing here is medical advice or a claim that AOD-9604 is safe or effective for any use.
| Type | Status in Canada | |
|---|---|---|
| AOD-9604 | Modified hGH 177-191 fragment | Not authorized |
| HGH fragment 176-191 | Natural hGH 176-191 fragment | Research compound |
| Semaglutide | GLP-1 analogue | Authorized prescription drug |
See the semaglutide profile or compare peptides side by side.
AOD-9604 is not authorized by Health Canada as a drug, so it cannot legally be sold for human or animal use in Canada. This is general information, not legal advice. Read how peptides are regulated in Canada.
AOD-9604 is a synthetic peptide based on the tail end (amino acids 177 to 191) of human growth hormone, with a tyrosine added at the start for stability. It was designed to keep a fat-metabolism region of the hormone without its other effects. It is also known as Anti-Obesity Drug 9604, hGH fragment 177-191.
AOD-9604 is not authorized by Health Canada as a drug, so it cannot legally be sold for human or animal use in Canada. This is general information, not legal advice.
It is not authorized for human or animal use in Canada, and products sold online cannot be verified without a lot-matched third-party Certificate of Analysis.
They are closely related. HGH fragment 176-191 is the natural sequence, while AOD-9604 adds a tyrosine residue at the start for stability.
Yes. AOD-9604 is on the World Anti-Doping Agency (WADA) Prohibited List: Prohibited: S2 (growth hormone fragments).
39 amino acids (modified, lipidated) · 4731.3 g/mol
31 amino acids (modified, lipidated) · 4113.6 g/mol
This profile is for information only and is not medical advice. This profile is educational only and is not medical advice. See our full disclaimer.