Endocrine Research
CJC-1295 (No DAC) + Ipamorelin
29 + 5 amino acids · 3367.9 / 711.9 g/mol
WADA: prohibitedView
Sequence, molecular data, research status and testing standards for Sermorelin, written for Canadian researchers.
Sermorelin is a synthetic peptide made of the first 29 amino acids of human growth hormone-releasing hormone (GHRH), the shortest fragment that keeps the full activity of the natural hormone. It signals the pituitary gland to release growth hormone.
Sermorelin was marketed in the United States as a prescription diagnostic and treatment product (Geref) before the manufacturer discontinued it. It has been studied extensively as a tool for understanding the growth hormone axis, and it is the template for stabilized GHRH analogues such as CJC-1295 (no DAC) and tesamorelin.
What it is: A lab-made copy of the first part of the body's own signal to release growth hormone.
The plain-English story: A lab-made copy of the first part of your body's own 'release growth hormone' cue. It was once sold as a medicine in some countries and is now mostly used in research. It is not an approved medicine you can buy online in Canada, and it is banned in sport.
What it does in the body: It tells the body's master gland to release growth hormone.
What researchers are looking at: Once sold as a medicine in some countries. It is now mostly used in research.
What you may hear online: Videos often describe it as a gentler growth hormone option.
The straight story: It is not available as an approved product in Canada, and products sold online cannot be trusted.
The catch (where it stands in Canada): Not an approved medicine in Canada, so nobody can legally sell it to you as one. Also banned in sport.
Educational information only. Not medical advice, and not a claim that this peptide is safe or effective for any use.
Peptide Authority summarizes published research for educational purposes only. Nothing here is medical advice or a claim that Sermorelin is safe or effective for any use.
| Structure | Status | |
|---|---|---|
| Sermorelin | GHRH amino acids 1-29 | Formerly marketed; now mainly research |
| CJC-1295 (no DAC) | Stabilized GHRH 1-29 (Mod GRF 1-29) | Research peptide |
| Tesamorelin | Full GHRH 1-44 + protective group | Prescription drug (Egrifta) |
See the tesamorelin profile, the CJC-1295 + Ipamorelin profile or compare peptides side by side.
Sermorelin is a prescription-type drug where it has been authorized. It is not a product authorized for sale to the public in Canada, and drugs may only be sold through licensed pharmacies where authorized. Selling sermorelin for human use outside that system is illegal. This is general information, not legal advice. Read how peptides are regulated in Canada.
Sermorelin is a synthetic peptide made of the first 29 amino acids of human growth hormone-releasing hormone (GHRH), the shortest fragment that keeps the full activity of the natural hormone. It signals the pituitary gland to release growth hormone. It is also known as GRF 1-29, GHRH(1-29).
Sermorelin is a prescription-type drug where it has been authorized. It is not a product authorized for sale to the public in Canada, and drugs may only be sold through licensed pharmacies where authorized. Selling sermorelin for human use outside that system is illegal. This is general information, not legal advice.
Prescription drugs should only come from a licensed pharmacy with a prescription. Products sold online as sermorelin are unregulated and their contents cannot be verified. Speak with a licensed healthcare professional about options.
All three are GHRH analogues. Sermorelin is the first 29 amino acids of GHRH. CJC-1295 (no DAC) is a stabilized version of the same 29 amino acids. Tesamorelin is the full 44-amino-acid sequence with a protective group, and is the only one currently marketed as a prescription drug.
Yes. Sermorelin is on the World Anti-Doping Agency (WADA) Prohibited List: Prohibited: S2 (GHRH and its analogues).
29 + 5 amino acids · 3367.9 / 711.9 g/mol
29 amino acids (modified) · 3647.2 g/mol
This profile is for information only and is not medical advice. This profile is educational only and is not medical advice. See our full disclaimer.