MOTS-c: Peptide Profile
Sequence, molecular data, research status and testing standards for MOTS-c — written for Canadian researchers.
What Is MOTS-c?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA, of interest in metabolic and cellular research.
What the Research Says About MOTS-c
First described in 2015, MOTS-c is studied in cell and animal models for its role in mitochondrial signalling, metabolic regulation and cellular stress responses. Human research is at an early stage.
Peptide Authority summarizes published research for educational purposes only. Nothing here is medical advice or a claim that MOTS-c is safe or effective for any use.
MOTS-c Storage & Handling
Lyophilized (freeze-dried) MOTS-c is most stable frozen at −20°C or colder for long-term storage, or refrigerated at 2–8°C for short periods. Keep vials sealed, dry and away from light, and allow them to reach room temperature before opening to prevent condensation.
What to Look for in a MOTS-c Certificate of Analysis
- HPLC purity of 98–99% or higher, shown as a chromatogram with one dominant peak
- Mass spectrometry with an observed mass matching 2174.6 g/mol
- A lot number that matches the label on your vial
- An independent, named laboratory and a recent test date
Learn more in our guide to peptide lab testing and COAs.
Is MOTS-c Legal in Canada?
MOTS-c is not authorized by Health Canada as a drug. It may only be sold in Canada as a research chemical for in-vitro laboratory use — not for human or animal consumption. Read how peptides are regulated in Canada.
MOTS-c FAQs
What is MOTS-c?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA, of interest in metabolic and cellular research. It is also known as Mitochondrial open reading frame of the 12S rRNA type-c.
Is MOTS-c legal in Canada?
MOTS-c is not authorized by Health Canada as a drug, so it cannot legally be sold for human or animal use. In Canada it is sold as a research chemical for in-vitro laboratory use only. This is general information, not legal advice.
Where can I buy MOTS-c in Canada?
Peptide Authority supplies HPLC-tested, lot-coded MOTS-c for research use, now serving Edmonton with Canada-wide shipping coming soon. Wherever you buy, insist on a third-party COA that matches the lot number on your vial.
How should MOTS-c be stored?
Store lyophilized MOTS-c frozen at −20°C for long-term stability or refrigerated at 2–8°C short-term, protected from light and moisture.
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Educational Content & Research Use Only
This profile is for information only and is not medical advice. Products sold by Peptide Authority are for in-vitro laboratory research only and are not for human or animal consumption. See our full disclaimer.